Case Report: Early Transplant Rejection of a Methanol-Intoxicated Donor Heart in a Young Female Patient. A Diagnostic Approach With CMR, Cardiac Biopsy, and Genetic Risk Assessment.

• 影响指数: 8.786
• 发表时间: 2020
• 来源期刊: Front Immunol
• DOI: 10.3389/fimmu.2020.575635
• PMID: 33692775
• 文章类型: Case Reports
• 中科院分区: Q2
• 方向: 医学
• 作者列表: Stoiber L,Schoenrath F,Knosalla C,Milting H,Klingel K,Tschöpe C,Tanacli R,Gebker R,Berger A,Pieske B,Kelle S

关键词: cardiac magnetic resonance imaging (CMR); cardiomyopathy; gene sequence; heart transplantation; mapping - magnetic resonance imaging

Mesh: Alcoholic Intoxication / complications diagnosis; Biopsy; Cardiomyopathy, Dilated / diagnosis physiopathology surgery; Diagnosis, Differential; Donor Selection; Female; Genetic Predisposition to Disease; Graft Rejection / diagnosis etiology genetics therapy; Heart Failure / diagnosis physiopathology surgery; Heart Transplantation / adverse effects; Humans; Magnetic Resonance Imaging; Methanol / poisoning; Middle Aged; Molecular Diagnostic Techniques; Predictive Value of Tests; Risk Assessment; Risk Factors; Time Factors; Tissue Donors; Treatment Outcome; Young Adult

Abstract

This case report describes the contributions of multimodality imaging, cardiac biopsy, and genetic sequencing to the diagnosis and management of heart transplant rejection in a 23-year old patient with dilated cardiomyopathy.