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Abstract：
Three new tryptamine derivatives diaporols T-V (1-3) were isolated by adding tryptamine into the culture of Diaporthe sp., a fungus obtained from the leaves of Rhizophora stylosa. The structures of these compounds were elucidated by NMR spectroscopy and high resolution mass spectroscopic data. Among them, compound 1 showed moderate cytotoxic activity against SW480 cancer cell with IC50 9.84 μM.
摘要：
通过将色胺添加到Diaporthesp的培养物中，分离出三种新的色胺衍生物DiaporolsT-V（1-3）。,从根茎叶获得的真菌。通过NMR光谱和高分辨率质谱数据阐明了这些化合物的结构。其中,化合物1对SW480癌细胞显示中等的细胞毒活性,IC50为9.84μM。
