%0 Journal Article
%T Generation of tryptamine derivatives through biotransformation by Diaporthe sp.
%A Chen CJ
%A Li D
%A Yu KY
%A Zhou MM
%J J Asian Nat Prod Res
%V 0
%N 0
%D Jan 2021 12
%M 33432842
%F 1.61
%R 10.1080/10286020.2020.1866560
%X Three new tryptamine derivatives diaporols T-V (1-3) were isolated by adding tryptamine into the culture of Diaporthe sp., a fungus obtained from the leaves of Rhizophora stylosa. The structures of these compounds were elucidated by NMR spectroscopy and high resolution mass spectroscopic data. Among them, compound 1 showed moderate cytotoxic activity against SW480 cancer cell with IC50 9.84 μM.