Mesh : Adolescent Cheese Child Diagnostic Techniques, Digestive System Eggs Female Food Gastric Emptying Humans Male Meals Radionuclide Imaging / methods Radiopharmaceuticals Reference Values Young Adult

来  源:   DOI:10.14309/ajg.0000000000000831   PDF(Sci-hub)

Abstract:
Adult standards for gastric emptying scintigraphy, including the type of meal and range of normative values for percent gastric emptying, are routinely used in pediatric practice, but to date have not been validated. The purpose of this study is to determine whether the use of adult criteria for gastric emptying scintigraphy is valid for children and whether alternative nonstandard meals can also be offered based on these criteria.
This retrospective study analyzed patients (n = 1,151 total) who underwent solid-phase gastric emptying scintigraphy. Patients were stratified into normal and delayed gastric emptying cohorts based on adult criteria, i.e., with normal gastric emptying defined as ≤10% gastric retention at 4 hours. Patients were further stratified based on the type of meal, namely complete or partial adult standard meals or alternative cheese-based meals. Percent gastric retention values at 1, 2, 3, and 4 hours were compared.
The median (95% upper reference limit) percentage gastric retention values for the complete standard meal were 72% (93%) at 1 hour, 39% (65%) at 2 hours, 15% (33%) at 3 hours, and 6% (10 %) at 4 hours. By comparison, the values for cheese-based meals were 60% (87%) at 1 hour, 29% (61%) at 2 hours, 10% (30%) at 3 hours, and 5% (10%) at 4 hours. Consumption of at least 50% of the standard meal yielded similar retention percentages; 68% (89%) at 1 hour, 32% (57%) at 2 hours, 10% (29%) at 3 hours, and 5% (10%) at 4 hours. There were no significant age- or sex-specific differences using the adult criteria.
The adult normative standards for gastric emptying scintigraphy are applicable for use in the pediatric population. These same standards can be also be applied to nonstandard meal options, including cheese-based alternative meals and partial standard meals.
摘要:
成人胃排空显像标准,包括膳食类型和胃排空百分比的标准值范围,通常用于儿科实践,但迄今为止尚未验证。这项研究的目的是确定使用成人标准进行胃排空闪烁显像是否对儿童有效,以及是否也可以根据这些标准提供替代的非标准膳食。
这项回顾性研究分析了接受固相胃排空闪烁显像的患者(n=1,151)。根据成人标准将患者分为正常和延迟胃排空队列,即,正常胃排空定义为4小时胃潴留≤10%。患者根据膳食类型进一步分层,即完全或部分成人标准膳食或替代奶酪膳食。比较1、2、3和4小时的胃滞留百分比值。
在1小时时,完整标准餐的中位(95%参考上限)胃滞留百分比值为72%(93%),39%(65%)在2小时,15%(33%)在3小时,和6%(10%)在4小时。相比之下,以奶酪为基础的膳食在1小时时为60%(87%),29%(61%)在2小时,10%(30%)在3小时,和5%(10%)在4小时。消耗至少50%的标准餐产生类似的保留百分比;68%(89%)在1小时,32%(57%)在2小时,10%(29%)在3小时,和5%(10%)在4小时。使用成人标准没有显著的年龄或性别特异性差异。
成人胃排空闪烁显像标准适用于儿科人群。这些相同的标准也可以应用于非标准膳食选择,包括基于奶酪的替代餐和部分标准餐。
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