Gridlock 转录阻遏物通过限制赖氨酸甲基转移酶的表达来阻碍脊椎动物的心脏再生。
关键词: Cardiomyocyte proliferation Grl Heart regeneration Hey2 Lysine methyltransferase Zebrafish
Mesh : Animals Animals, Newborn Basic Helix-Loop-Helix Transcription Factors / genetics Cell Differentiation / genetics Cell Proliferation / genetics Heart / physiology Lysine / genetics Methyltransferases / genetics Myocardium / metabolism Myocytes, Cardiac / metabolism Phosphorylation / genetics Regeneration / genetics STAT3 Transcription Factor / genetics Signal Transduction / genetics Transcription, Genetic / genetics Vertebrates / genetics Zebrafish / genetics Zebrafish Proteins / genetics
来 源:
DOI:10.1242/dev.190678
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