关键词: Acute lymphoblastic leukaemia Biopharmaceutical Error-prone polymerase chain reaction Human proteases L-asparaginase Protein stability
Mesh : Amino Acid Sequence Animals Antineoplastic Agents / chemistry pharmacology therapeutic use Asparaginase / chemistry pharmacology therapeutic use Biological Products / chemistry pharmacology therapeutic use Cattle Cell Survival / drug effects physiology Chickens Dose-Response Relationship, Drug Escherichia coli Female Horses Humans Immunogenetic Phenomena / drug effects physiology Jurkat Cells Lysosomes / chemistry immunology Mice Mice, Inbred BALB C Peptide Hydrolases / chemistry pharmacology therapeutic use Precursor Cell Lymphoblastic Leukemia-Lymphoma / drug therapy immunology Protein Structure, Secondary
来 源:
DOI:10.1016/j.bcp.2020.114230
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