Mesh : Adolescent Adult Aftercare Aged Anti-Bacterial Agents / administration & dosage therapeutic use Bronchoalveolar Lavage / methods Burkholderia Infections / complications immunology microbiology Burkholderia cepacia complex / genetics isolation & purification pathogenicity Community-Acquired Infections / diagnosis microbiology Diagnosis, Differential Endoscopic Ultrasound-Guided Fine Needle Aspiration / methods Female Humans Immunocompetence / immunology Male Middle Aged Onions / microbiology Plant Diseases / microbiology Pneumonia / diagnosis drug therapy microbiology pathology Tomography, X-Ray Computed / methods Treatment Outcome Trimethoprim, Sulfamethoxazole Drug Combination / administration & dosage therapeutic use

来  源:   DOI:10.4081/monaldi.2020.1484   PDF(Sci-hub)

Abstract:
Burkholderia cepacia complex consists of highly antibiotic resistant gram negative bacilli that are plant symbionts and also potential agents of human infection.  This bacterial family\'s claim to fame in clinical medicine is as the scourge of cystic fibrosis patients, in whom it is a notorious respiratory pathogen.  Outside of cystic fibrosis, it rarely comes to mind as an etiology of community acquired pneumonia with or without lung cavitation in immunocompetent hosts.  We describe a case of an otherwise healthy, community-dwelling man who presented with subacute cavitary lung disease, the causative organism of which turned out to be Burkholderia cepacia complex.  Our report is accompanied by a review of the literature, which identified an additional eleven cases in the same category.  We analyze all of the available cases for the emergence of any identifiable patterns or peculiarities.
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