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Abstract：
BACKGROUND: The elderly population is the group most threatened by COVID-19, with the highest mortality rates. This study aims to analyse the case fatality of COVID-19 in a cohort of patients with degenerative dementia.
METHODS: We conducted a descriptive case-control study of a sample of patients diagnosed with primary neurodegenerative dementia.
RESULTS: Twenty-four of the 88 patients with COVID-19 included in the study died: 10/23 (43.4%) patients diagnosed with dementia and 14/65 (21.5%) controls; this difference was statistically significant.
CONCLUSIONS: Our results suggest that case fatality of COVID-19 is significantly higher among patients with primary degenerative dementia than in other patients with similar mean ages and comorbidities.
METHODS: We conducted a descriptive case-control study of a sample of patients diagnosed with primary neurodegenerative dementia.
RESULTS: Twenty-four of the 88 patients with COVID-19 included in the study died: 10/23 (43.4%) patients diagnosed with dementia and 14/65 (21.5%) controls; this difference was statistically significant.
CONCLUSIONS: Our results suggest that case fatality of COVID-19 is significantly higher among patients with primary degenerative dementia than in other patients with similar mean ages and comorbidities.
摘要：
背景：老年人群是受COVID-19威胁最大的群体，死亡率最高。这项研究旨在分析一组退行性痴呆患者中COVID-19的病死率。
方法：我们对被诊断为原发性神经退行性痴呆的患者样本进行了描述性病例对照研究。
结果：纳入研究的88例COVID-19患者中有24例死亡：10/23（43.4％）被诊断为痴呆症的患者和14/65（21.5％）的对照组；这种差异具有统计学意义。
结论：我们的结果表明，原发性退行性痴呆患者的COVID-19病死率明显高于其他具有相似平均年龄和合并症的患者。
方法：我们对被诊断为原发性神经退行性痴呆的患者样本进行了描述性病例对照研究。
结果：纳入研究的88例COVID-19患者中有24例死亡：10/23（43.4％）被诊断为痴呆症的患者和14/65（21.5％）的对照组；这种差异具有统计学意义。
结论：我们的结果表明，原发性退行性痴呆患者的COVID-19病死率明显高于其他具有相似平均年龄和合并症的患者。
