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Abstract：
BACKGROUND: Cerebral venous sinus thrombosis in children is a rare but potentially fatal complication of acute mastoiditis, one of the most common pediatric infectious diseases. Due to its subtle clinical presentation, suspicion is essential for a prompt diagnosis and appropriate management. Unfortunately, no standard treatment options are available. To discuss the possible clinical presentation, microbiology, and management, we here report the case of a child with otogenic cerebral venous sinus thrombosis and perform a literature review starting from 2011.
METHODS: The child, a 10-months-old male, presented clinical signs of right acute otitis media and mastoiditis. Brain computed tomography scan detected right sigmoid and transverse sinus thrombosis, as well as a subperiosteal abscess. Fusobacterium necrophorum and Haemophilus Influentiae were detected on cultural sampling. A multidisciplinary approach along with a combination of medical and surgical therapy allowed the patient\'s full recovery.
CONCLUSIONS: Cerebral venous sinus thrombosis is a rare but severe complication of acute otitis media and mastoiditis. The management of this pathological condition is always challenging and an interdisciplinary approach is frequently required. Current therapeutic options include a combination of medical and surgical therapy. A patient-centered approach should guide timing and treatment management.
METHODS: The child, a 10-months-old male, presented clinical signs of right acute otitis media and mastoiditis. Brain computed tomography scan detected right sigmoid and transverse sinus thrombosis, as well as a subperiosteal abscess. Fusobacterium necrophorum and Haemophilus Influentiae were detected on cultural sampling. A multidisciplinary approach along with a combination of medical and surgical therapy allowed the patient\'s full recovery.
CONCLUSIONS: Cerebral venous sinus thrombosis is a rare but severe complication of acute otitis media and mastoiditis. The management of this pathological condition is always challenging and an interdisciplinary approach is frequently required. Current therapeutic options include a combination of medical and surgical therapy. A patient-centered approach should guide timing and treatment management.
摘要：
背景：儿童脑静脉窦血栓形成是一种罕见但可能致命的急性乳突炎并发症，最常见的儿科传染病之一。由于其微妙的临床表现，怀疑是必要的及时诊断和适当的管理。不幸的是,没有标准的治疗选择。讨论可能的临床表现，微生物学,和管理,我们在此报告1例儿童耳源性脑静脉窦血栓形成，并从2011年开始进行文献复习。
方法：孩子，一个10个月大的男性,呈现右侧急性中耳炎和乳突炎的临床体征。脑部计算机断层扫描扫描发现右乙状结肠和横窦血栓形成，以及骨膜下脓肿.在培养采样中检测到坏死梭杆菌和流感嗜血杆菌。多学科方法以及药物和手术治疗的结合使患者完全康复。
结论：脑静脉窦血栓形成是急性中耳炎和乳突炎的一种罕见但严重的并发症。这种病理状况的管理总是具有挑战性的，并且经常需要跨学科的方法。当前的治疗选择包括医学和手术治疗的组合。以患者为中心的方法应指导时机和治疗管理。
方法：孩子，一个10个月大的男性,呈现右侧急性中耳炎和乳突炎的临床体征。脑部计算机断层扫描扫描发现右乙状结肠和横窦血栓形成，以及骨膜下脓肿.在培养采样中检测到坏死梭杆菌和流感嗜血杆菌。多学科方法以及药物和手术治疗的结合使患者完全康复。
结论：脑静脉窦血栓形成是急性中耳炎和乳突炎的一种罕见但严重的并发症。这种病理状况的管理总是具有挑战性的，并且经常需要跨学科的方法。当前的治疗选择包括医学和手术治疗的组合。以患者为中心的方法应指导时机和治疗管理。
