{Reference Type}: Case Reports
{Title}: Pediatric otogenic cerebral venous sinus thrombosis: a case report and a literature review.
{Author}: Castellazzi ML;di Pietro GM;Gaffuri M;Torretta S;Conte G;Folino F;Aleo S;Bosis S;Marchisio P;
{Journal}: Ital J Pediatr
{Volume}: 46
{Issue}: 1
{Year}: Sep 2020 3
{Factor}: 3.288
{DOI}: 10.1186/s13052-020-00882-9
{Abstract}: <B>BACKGROUND: </B>Cerebral venous sinus thrombosis in children is a rare but potentially fatal complication of acute mastoiditis, one of the most common pediatric infectious diseases. Due to its subtle clinical presentation, suspicion is essential for a prompt diagnosis and appropriate management. Unfortunately, no standard treatment options are available. To discuss the possible clinical presentation, microbiology, and management, we here report the case of a child with otogenic cerebral venous sinus thrombosis and perform a literature review starting from 2011.<BR><B>METHODS: </B>The child, a 10-months-old male, presented clinical signs of right acute otitis media and mastoiditis. Brain computed tomography scan detected right sigmoid and transverse sinus thrombosis, as well as a subperiosteal abscess. Fusobacterium necrophorum and Haemophilus Influentiae were detected on cultural sampling. A multidisciplinary approach along with a combination of medical and surgical therapy allowed the patient's full recovery.<BR><B>CONCLUSIONS: </B>Cerebral venous sinus thrombosis is a rare but severe complication of acute otitis media and mastoiditis. The management of this pathological condition is always challenging and an interdisciplinary approach is frequently required. Current therapeutic options include a combination of medical and surgical therapy. A patient-centered approach should guide timing and treatment management.