关键词: antibiotics metal coordination metallo-β-lactamase (MBL) x-ray crystallography
Mesh : Bacillus subtilis / enzymology Bacterial Proteins / chemistry genetics metabolism Binding Sites Catalytic Domain Coordination Complexes / chemistry Crystallography, X-Ray Drug Resistance, Multiple, Bacterial Endoribonucleases / chemistry genetics metabolism Evolution, Molecular Flavobacteriaceae / enzymology Models, Molecular Mutagenesis, Site-Directed Protein Binding Protein Conformation Structure-Activity Relationship Water Zinc / metabolism beta-Lactamases / chemistry genetics metabolism
来 源:
DOI:10.3390/ijms21144926
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