Evidence Review for Centers for Disease Control and Prevention Guidance Development on Laboratory Testing to Detect Treponema pallidum Infection (Syphilis).

疾病控制和预防中心关于检测梅毒螺旋体感染 （ 梅毒 ） 的实验室检测指导开发的证据审查。

• 影响指数: 20.999
• 发表时间: 06 2020 24
• 来源期刊: Clin Infect Dis
• DOI: 10.1093/cid/ciaa348
• PMID: 32578867
• 文章类型: Journal Article
• 中科院分区: Q1
• 方向: 医学
• 作者列表: Kersh EN,Workowski KA

关键词: Treponema pallidum direct detection; serology; syphilis diagnostics; systematic review

Mesh: Antibodies, Bacterial; Centers for Disease Control and Prevention, U.S.; Clinical Laboratory Techniques / standards; Humans; Syphilis / diagnosis epidemiology; Syphilis Serodiagnosis; Treponema pallidum / genetics; United States

Abstract

The articles in this supplement address key questions on syphilis diagnostics, provide reference tables of test performances, and discuss optimal specimens and knowledge gaps. Laboratory-developed genetic direct detection tests could be most useful at the point of care and add to the currently available serologic methods of nontreponemal and treponemal tests.

摘要

本增刊中的文章涉及梅毒诊断的关键问题，提供测试性能的参考表，并讨论最佳标本和知识差距。实验室开发的遗传直接检测测试在护理点可能是最有用的，并且是当前可用的非螺旋体和螺旋体测试的血清学方法。