%0 Journal Article %T Evidence Review for Centers for Disease Control and Prevention Guidance Development on Laboratory Testing to Detect Treponema pallidum Infection (Syphilis). %A Kersh EN %A Workowski KA %J Clin Infect Dis %V 71 %N 0 %D 06 2020 24 %M 32578867 %F 20.999 %R 10.1093/cid/ciaa348 %X The articles in this supplement address key questions on syphilis diagnostics, provide reference tables of test performances, and discuss optimal specimens and knowledge gaps. Laboratory-developed genetic direct detection tests could be most useful at the point of care and add to the currently available serologic methods of nontreponemal and treponemal tests.