关键词: ATPase Aquifex aeolicus Bergerat fold DNA mismatch repair DNA-binding protein Lynch syndrome MutL X-ray crystal structure X-ray crystallography cancer postmeiotic segregation increased 2 (PMS2) protein stability
Mesh : Adenosine Triphosphate / metabolism Amino Acid Sequence Aquifex / chemistry genetics Bacterial Proteins / chemistry genetics Binding Sites Colorectal Neoplasms, Hereditary Nonpolyposis / genetics Crystallography, X-Ray DNA Mismatch Repair Humans Models, Molecular MutL Proteins / chemistry genetics Mutation Protein Conformation Protein Domains
来 源:
DOI:10.1074/jbc.RA120.013576
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