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Abstract：
Chagas disease is among the neglected tropical diseases recognized by the World Health Organization that have received insufficient attention from governments and health agencies. Chagas disease is endemic in 21 Latin America regions. Due to globalization and increased migration, it has crossed borders and reached other regions including North America and Europe. The clinical presentation of the disease is highly variable, from general symptoms to severe cardiac involvement that can culminate in heart failure. Chagas heart disease is multifactorial, and can include dilated cardiomyopathy, thromboembolic phenomena, and arrhythmias that may lead to sudden death. Diagnosis is by methods such as enzyme-linked immunosorbent assay (ELISA) and the degree of cardiac involvement should be investigated with complementary exams including ECG, chest radiography and electrophysiological study. There have been insufficient studies on which to base specific treatment for heart failure due to Chagas disease. Treatment should therefore be derived from guidelines for heart failure that are not specific for this disease. Heart transplantation is a viable option with satisfactory success rates that has improved survival.
摘要：
恰加斯病是世界卫生组织公认的被忽视的热带病之一，受到政府和卫生机构的重视不足。查加斯病在21个拉丁美洲地区流行。由于全球化和移民增加，它已经越过边界，到达了包括北美和欧洲在内的其他地区。该疾病的临床表现是高度可变的，从一般症状到严重的心脏受累，最终导致心力衰竭。查加斯心脏病是多因素的，可能包括扩张型心肌病，血栓栓塞现象,和可能导致猝死的心律失常。通过酶联免疫吸附测定（ELISA）等方法进行诊断，心脏受累的程度应通过包括ECG在内的补充检查进行调查。胸片和电生理研究。目前还没有足够的研究来建立针对由Chagas病引起的心力衰竭的特定治疗的基础。因此，治疗应该来自心力衰竭的指南，这些指南对这种疾病没有特异性。心脏移植是一种可行的选择，成功率令人满意，可以提高生存率。
