全基因组分析确定了 NURR1 控制的新突触形成和人神经干细胞细胞周期阻滞的网络。
关键词: NURR-1 dopaminergic neurogenesis gene expression profiling human neural stem cell
Mesh : Animals Base Sequence Cell Cycle Checkpoints / genetics Cell Cycle Proteins / genetics metabolism Cell Differentiation / genetics Cell Line Cell Lineage / genetics Cell Movement / genetics Gene Ontology Gene Regulatory Networks Genome-Wide Association Study Humans Mesencephalon / embryology Mice Neural Stem Cells / cytology metabolism Neurogenesis / genetics Nuclear Receptor Subfamily 4, Group A, Member 2 / genetics metabolism Parkinson Disease / genetics Promoter Regions, Genetic / genetics Reproducibility of Results Synapses / metabolism Transcriptional Activation / genetics
来 源:
DOI:10.14348/molcells.2020.0071
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