Rare non-Hodgkin lymphoma of childhood and adolescence: A consensus diagnostic and therapeutic approach to pediatric-type follicular lymphoma, marginal zone lymphoma, and nonanaplastic peripheral T-cell lymphoma.

• 影响指数: 3.838
• 发表时间: 08 2020
• 来源期刊: Pediatr Blood Cancer
• DOI: 10.1002/pbc.28416
• PMID: 32452165
• 文章类型: Journal Article
• 中科院分区: Q3
• 方向: 医学
• 作者列表: Attarbaschi A,Abla O,Arias Padilla L,Beishuizen A,Burke GAA,Brugières L,Bruneau J,Burkhardt B,d'Amore ESG,Klapper W,Kontny U,Pillon M,Taj M,Turner SD,Uyttebroeck A,Woessmann W,Mellgren K

关键词: follicular lymphoma; marginal zone lymphoma; non-Hodgkin lymphoma; peripheral T-cell lymphoma; rare

Mesh: Adolescent; Allografts; Child; Child, Preschool; Female; Hematopoietic Stem Cell Transplantation; Humans; Infant; Lymphoma, B-Cell, Marginal Zone / diagnosis therapy; Lymphoma, Follicular / diagnosis therapy; Lymphoma, T-Cell, Peripheral / diagnosis therapy; Male

Abstract

Pediatric-type follicular (PTFL), marginal zone (MZL), and peripheral T-cell lymphoma (PTCL) account each for <2% of childhood non-Hodgkin lymphoma. We present clinical and histopathological features of PTFL, MZL, and few subtypes of PTCL and provide treatment recommendations. For localized PTFL and MZL, watchful waiting after complete resection is the therapy of choice. For PTCL, therapy is subtype-dependent and ranges from a block-like anaplastic large cell lymphoma (ALCL)-derived and, alternatively, leukemia-derived therapy in PTCL not otherwise specified and subcutaneous panniculitis-like T-cell lymphoma to a block-like mature B-NHL-derived or, preferentially, ALCL-derived treatment followed by hematopoietic stem cell transplantation in first remission in hepatosplenic and angioimmunoblastic T-cell lymphoma.