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Abstract：
People with schizophrenia have an increased risk of developing cardiometabolic diseases and a reduced life expectancy. Studies conducted mainly in Western settings report low amounts of activity and poor levels of fitness in this population. This study aims to compare physical fitness and activity levels between people with schizophrenia/healthy matched controls and investigate potential associations between these variables. A cross-sectional study was conducted with 57 community-dwelling people with schizophrenia and 57 age-, gender- and body mass index (BMI)-matched controls. Participants completed the international physical activity questionnaire and the Young Men\'s Christian Association (YMCA) fitness assessment protocol with accompanying cardiovascular/lung function tests. Cardiorespiratory fitness was significantly better in healthy matched controls than individuals with schizophrenia in all areas (all p < 0.05, d = 0.38 to 1.06). Performance in best trunk flexion, half sit-ups and one-minute pulse recovery following the three-min step test were significantly worse in the schizophrenia group (all p < 0001, d = 0.76 to 1.04). Higher levels of weekly moderate activity (t = -2.66, p = 0.009) and total weekly activity levels (t = -2.013, p = 0.047) were reported by the healthy controls. Levels of vigorous activity were significantly correlated with some areas of lung functioning in the schizophrenia group (all p < 0.05). The findings show that Chinese people with schizophrenia have significantly poorer fitness than matched healthy controls, demonstrating the need to provide timely effective exercise-based interventions as a matter of routine to attenuate the risk of developing chronic physical illnesses.
摘要：
精神分裂症患者患心脏代谢疾病的风险增加，预期寿命缩短。主要在西方环境中进行的研究报告，该人群的活动量低，健身水平差。这项研究旨在比较精神分裂症患者/健康匹配对照组之间的身体素质和活动水平，并研究这些变量之间的潜在关联。一项横断面研究是对57名社区居住的精神分裂症患者和57名年龄-性别和体重指数（BMI）匹配的对照。参与者完成了国际体育锻炼问卷和基督教青年会（YMCA）健身评估方案，并进行了心血管/肺功能测试。在所有领域，健康匹配的对照组的心肺适应性明显优于精神分裂症患者（所有p<0.05，d=0.38至1.06）。在最佳躯干屈曲中的表现，在三分钟台阶试验后，半仰卧起坐和一分钟脉搏恢复在精神分裂症组中明显更差（所有p<0001，d=0.76至1.04）。健康对照报告较高水平的每周中等活动(t=-2.66,p=0.009)和总每周活动水平(t=-2.013,p=0.047)。在精神分裂症组中，剧烈活动水平与某些肺功能区域显着相关（均p<0.05）。研究结果表明，中国精神分裂症患者的健康状况明显低于健康对照组，证明有必要提供及时有效的基于运动的干预措施，作为日常事项，以减轻发展为慢性身体疾病的风险。
