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Abstract：
OBJECTIVE: The aim of the study was to analyze morphological parameters of apparently functional filtering blebs with anterior segment optical coherence tomography at 1 month post trabeculectomy and to correlate these parameters with intraocular pressure at 6 months of follow-up to predict the short-term success of trabeculectomy.
METHODS: In this cross-sectional, descriptive study, apparently functional blebs were evaluated using anterior segment optical coherence tomography with crossline scans after 1 month of trabeculectomy.
RESULTS: A total of 55 eyes of 55 cases with mean age 49.29 ± 13.72 years were included in the study. On anterior segment optical coherence tomography examination, the mean bleb height and mean bleb wall thickness, subconjunctival fluid space, and scleral flap thickness were 1.45 ± 0.39 mm, 0.63 ± 0.25 mm, 0.64 ± 0.26 mm, and 0.45 ± 0.068 mm, respectively. There was statistically significant negative correlation between intraocular pressure at 1 month and bleb height (r = -0.25, p = 0.05). There was statistically significant negative correlation between extent of cavity and intraocular pressure at 6 months (r = -0.318, p = 0.018). Bleb height showed significant negative correlation with supra-scleral space (r = -0.31, p = 0.02). Multi reflective bleb walls showed statistically significant increased chances of successful functioning blebs at 6 months as compared to uniform wall reflectivity (p = 0.00).Bleb function was successful in 37 (67.3%) and unsuccessful in 18 (32.7%) in short term of 6 months of follow-up.
CONCLUSIONS: Bleb walls with multiform wall reflectivity on anterior segment optical coherence tomography at 1 month post trabeculectomy show increased chances of success of functioning filtering bleb at 6 months. Bleb wall characteristics on anterior segment optical coherence tomography at 1 month can predict the short-term success of blebs at 6 months.
METHODS: In this cross-sectional, descriptive study, apparently functional blebs were evaluated using anterior segment optical coherence tomography with crossline scans after 1 month of trabeculectomy.
RESULTS: A total of 55 eyes of 55 cases with mean age 49.29 ± 13.72 years were included in the study. On anterior segment optical coherence tomography examination, the mean bleb height and mean bleb wall thickness, subconjunctival fluid space, and scleral flap thickness were 1.45 ± 0.39 mm, 0.63 ± 0.25 mm, 0.64 ± 0.26 mm, and 0.45 ± 0.068 mm, respectively. There was statistically significant negative correlation between intraocular pressure at 1 month and bleb height (r = -0.25, p = 0.05). There was statistically significant negative correlation between extent of cavity and intraocular pressure at 6 months (r = -0.318, p = 0.018). Bleb height showed significant negative correlation with supra-scleral space (r = -0.31, p = 0.02). Multi reflective bleb walls showed statistically significant increased chances of successful functioning blebs at 6 months as compared to uniform wall reflectivity (p = 0.00).Bleb function was successful in 37 (67.3%) and unsuccessful in 18 (32.7%) in short term of 6 months of follow-up.
CONCLUSIONS: Bleb walls with multiform wall reflectivity on anterior segment optical coherence tomography at 1 month post trabeculectomy show increased chances of success of functioning filtering bleb at 6 months. Bleb wall characteristics on anterior segment optical coherence tomography at 1 month can predict the short-term success of blebs at 6 months.
摘要：
目的：本研究的目的是在小梁切除术后1个月用眼前节光学相干断层扫描分析明显功能性滤过泡的形态学参数，并在随访6个月时将这些参数与眼压相关联，以预测小梁切除术的短期成功。
方法：在此横截面中，描述性研究，在小梁切除术1个月后,使用眼前节光学相干断层扫描和交叉线扫描评估明显功能性气泡.
结果：共55只眼，55例，平均年龄49.29±13.72岁。在眼前段光学相干断层扫描检查中，平均气泡高度和平均气泡壁厚，结膜下积液，巩膜瓣厚度为1.45±0.39mm，0.63±0.25mm,0.64±0.26mm,和0.45±0.068毫米，分别。1个月时眼压与气泡高度呈显著负相关(r=-0.25,p=0.05)。在6个月时，腔的范围与眼压之间存在统计学上的显着负相关（r=-0.318，p=0.018）。Bleb高度与巩膜上间隙呈显著负相关(r=-0.31,p=0.02)。与均匀的壁反射率相比，多反射泡壁在6个月时显示出统计学上显着增加的成功功能泡泡的机会（p=0.00）。在6个月的短期随访中，Bleb功能成功37例（67.3%），不成功18例（32.7%）。
结论：小梁切除术后1个月，在前节光学相干断层扫描上，具有多种形式的壁反射率的Bleb壁显示，在6个月时功能滤过泡成功的机会增加。1个月前段光学相干断层扫描的气泡壁特征可以预测6个月时气泡的短期成功。
方法：在此横截面中，描述性研究，在小梁切除术1个月后,使用眼前节光学相干断层扫描和交叉线扫描评估明显功能性气泡.
结果：共55只眼，55例，平均年龄49.29±13.72岁。在眼前段光学相干断层扫描检查中，平均气泡高度和平均气泡壁厚，结膜下积液，巩膜瓣厚度为1.45±0.39mm，0.63±0.25mm,0.64±0.26mm,和0.45±0.068毫米，分别。1个月时眼压与气泡高度呈显著负相关(r=-0.25,p=0.05)。在6个月时，腔的范围与眼压之间存在统计学上的显着负相关（r=-0.318，p=0.018）。Bleb高度与巩膜上间隙呈显著负相关(r=-0.31,p=0.02)。与均匀的壁反射率相比，多反射泡壁在6个月时显示出统计学上显着增加的成功功能泡泡的机会（p=0.00）。在6个月的短期随访中，Bleb功能成功37例（67.3%），不成功18例（32.7%）。
结论：小梁切除术后1个月，在前节光学相干断层扫描上，具有多种形式的壁反射率的Bleb壁显示，在6个月时功能滤过泡成功的机会增加。1个月前段光学相干断层扫描的气泡壁特征可以预测6个月时气泡的短期成功。
