Angelman 综合征人类神经元模型的钾通道功能障碍。
Mesh : Angelman Syndrome / metabolism physiopathology Animals Calcium Channels, N-Type / metabolism Epilepsy / metabolism Humans Mice Models, Neurological Neurons / drug effects metabolism Organoids Potassium Channel Blockers / pharmacology therapeutic use Seizures / metabolism Ubiquitin-Protein Ligases / genetics metabolism Ubiquitination
来 源:
DOI:10.1126/science.aav5386
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