In patients in the early ambulatory stage, clinical symptoms, quantitative muscle ultrasound of the orofacial muscles, and maximum bite force were assessed. The 6-Minute Walk Test (6MWT) was used to measure ambulatory capacity.
Eleven Duchenne and 11 Becker patients were included. Although Becker patients had a greater 6MWT distance than Duchenne patients, the occurrence of mastication and swallowing difficulties was similar. The temporalis muscle was significantly thicker in Becker patients.
Clinicians should be aware of dysphagia in both groups, even when ambulation is still well preserved.
在门诊早期的患者中,临床症状,口腔面部肌肉的定量肌肉超声,并评估了最大咬合力。6分钟步行测试(6MWT)用于测量步行能力。
包括11名Duchenne和11名Becker患者。尽管Becker患者的6MWT距离大于Duchenne患者,咀嚼和吞咽困难的发生是相似的。Becker患者的颞肌明显增厚。
临床医生应注意两组患者的吞咽困难,即使步行仍然保存完好。