关键词: Bisphosphonates Clinicopathological features Radiotherapy Secondary aneurysmal bone cyst Spine

Mesh : Adolescent Adult Bone Cysts, Aneurysmal / etiology surgery Embolization, Therapeutic Female Fibrous Dysplasia of Bone / complications surgery Giant Cell Tumor of Bone / complications surgery Hemangioma / complications surgery Humans Male Middle Aged Neurosurgical Procedures / methods Osteoblastoma / complications surgery Osteosarcoma / complications surgery Preoperative Care Prosthesis Failure Spinal Diseases / etiology surgery Spinal Fusion Spinal Neoplasms / complications surgery Surgical Wound Infection Young Adult

来  源:   DOI:10.1016/j.clineuro.2019.105595   PDF(Sci-hub)

Abstract:
Spinal secondary aneurysmal bone cyst (SABC) is extremely rare with few published reports available at present. Our aim is to explore the clinicopathologic features, surgical modalities and outcomes of spinal SABC.
A retrospective study of 33 patients with spinal SABC who were surgically treated in our center between 2010 and 2018 was performed. Clinical data, treatment options, complications and outcomes were analyzed.
Of the 33 patients, 12 were male and 21 were female, with a mean age of 32 years. Eleven lesions were located at the lumbar spine. The underlying lesions included giant cell tumor (GCT) (n = 20), osteoblastoma (n = 7), hemangiaoma (n = 3), fibrous dysplasia (n = 2) and osteosarcoma (n = 1). Preoperative selective arterial embolization was applied in 24 patients. All the patients were treated surgically through either subtotal resection (n = 1), piecemeal total resection (n = 21), or total en bloc resection (n = 11). Four patients experienced recurrence and one patient died during the follow-up period.
Spinal SABC is popular in the third and fourth decade of life with female predominance. GCT is the most common underlying lesion. Preoperative arterial embolization is recommended, while surgery is the mainstay of treatment for spinal SABC. En bloc resection is recommended for spinal SABCs especially when underlying tumor is aggressive or malignant.
摘要:
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