Hereditary spherocytosis with successful splenectomy in a pregnant black South African lady: a case report.

• 发表时间: 2019
• 来源期刊: Pan Afr Med J
• DOI: 10.11604/pamj.2019.33.288.18873
• PMID: 31692845
• 文章类型: Case Reports
• 作者列表: Elmezughi K,Ekpebegh C

关键词: Haemolytic anemia; South Africa; hereditary spherocytosis; massive splenomegaly; pregnancy; splenectomy

Mesh: Anemia, Hemolytic / etiology; Blacks; Female; Humans; Pregnancy; Pregnancy Complications, Hematologic / diagnosis surgery; South Africa; Spherocytosis, Hereditary / complications diagnosis surgery; Splenectomy / methods; Splenomegaly / etiology surgery; Young Adult

Abstract

Hereditary spherocytosis is a rare cause of chronic haemolytic anaemia. It is rarer in the black population with extremely few cases reported. Initial assessment of a patient with suspected disease should include documenting clinical features of chronic haemolysis and a family history. Its management in pregnancy is challenging and needs a multidisciplinary team. We report on a black South African woman with hereditary spherocytosis and massive splenomegaly presenting with severe haemolytic anaemia at 23rd week of pregnancy. She had a successful splenectomy.