关键词: Optic disc drusen optical coherence tomography angiography imaging modalities pseudopapilledema microvascular changes

Mesh : Adolescent Fluorescein Angiography / methods Fundus Oculi Humans Male Microvessels / pathology Multimodal Imaging / methods Nerve Fibers Optic Disk / pathology Optic Disk Drusen / diagnosis Retinal Ganglion Cells / pathology Retinal Vessels / pathology Tomography, Optical Coherence / methods Visual Acuity Visual Fields

来  源:   DOI:10.4274/tjo.galenos.2019.14194   PDF(Pubmed)

Abstract:
Optic disc drusen (ODD) is an important clinical entity that is sometimes misdiagnosed as papilledema because of elevated and blurred disc margins. A 17-year-old male who presented with headaches underwent detailed ophthalmological examination as well as colored fundus photography, B-scan ultrasonography (USG), fundus autofluorescence (FAF), optical coherence tomography (OCT), optical coherence tomography angiography (OCTA), and visual field testing. His visual acuity was 10/10 in both eyes. Fundus examination revealed bilateral blurred and elevated optic disc margins. Diagnosis of bilateral ODD was confirmed with B-scan USG. FAF imaging revealed hyperautofluorescent areas on both optic discs. Optic nerve head OCT scans showed elevated irregular disc borders and thinning of the retinal nerve fiber layer in both eyes. On visual field testing, loss of the nasal visual field was detected in the left eye. OCTA imaging showed focal capillary dropout, especially in the nasal peripapillary area, in both eyes and reduced peripapillary and macular vessel density. In this case report, we evaluated the clinical findings and the structural features of bilateral ODD with multimodal imaging modalities including OCTA.
摘要:
视盘玻璃疣(ODD)是一种重要的临床实体,由于椎间盘边缘升高和模糊,有时被误诊为乳头水肿。一名出现头痛的17岁男性接受了详细的眼科检查以及彩色眼底照相,B超(USG),眼底自发荧光(FAF),光学相干断层扫描(OCT),光学相干断层扫描血管造影(OCTA),和视野测试。他的双眼视力是10/10。眼底检查显示双侧视盘边缘模糊和升高。双侧ODD的诊断通过B扫描USG证实。FAF成像显示两个视盘上的高自发荧光区域。视神经头OCT扫描显示,双眼的椎间盘边界不规则升高,视网膜神经纤维层变薄。在视野测试中,在左眼中检测到鼻视野的丧失。OCTA成像显示局灶性毛细血管脱落,尤其是在鼻乳头周围区域,在双眼和减少的乳头周围和黄斑血管密度。在这个案例报告中,我们使用包括OCTA在内的多模态成像方式评估了双侧ODD的临床表现和结构特征.
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