Abstract：
Papillon-Lefèvre syndrome (PLS) is a rare genetic disorder characterized by palmoplantar keratosis and premature loss of primary and permanent dentition. Its onset can be as early as 1-4 years of age. The genetic disorder is mutation in the cathepsin C gene. Hereby, we discuss the fabrication of Cu-sil dentures for the prosthetic rehabilitation of a 14-year-old girl with PLS. The case report describes the procedure and associated relevant information regarding the management protocols.
摘要：
Papillon-Lefèvre综合征（PLS）是一种罕见的遗传性疾病，其特征是掌plant角化病以及原发性和永久性牙列的过早丧失。其发病可早至1-4岁。遗传性疾病是组织蛋白酶C基因的突变。特此,我们讨论了Cu-sil假牙的制造，用于14岁的PLS女孩的假肢康复。病例报告描述了有关管理方案的程序和相关信息。
