First case of laboratory-confirmed severe fever with thrombocytopenia syndrome disease revealed the risk of SFTSV infection in Xinjiang, China.

• 影响指数: 19.568
• 发表时间: 2019
• 来源期刊: Emerg Microbes Infect
• DOI: 10.1080/22221751.2019.1645573
• PMID: 31347462
• 文章类型: Case Reports
• 中科院分区: Q3
• 方向: 医学
• 作者列表: Zhu L,Yin F,Moming A,Zhang J,Wang B,Gao L,Ruan J,Wu Q,Wu N,Wang H,Deng F,Lu G,Shen S

关键词: Severe fever with thrombocytopenia syndrome virus; Xinjiang; exposure to ticks; first laboratory-confirmed case; virus isolation

Mesh: Animals; Bunyaviridae Infections / blood diagnosis transmission virology; China; Female; Humans; Middle Aged; Phlebovirus / classification genetics isolation & purification physiology; Phylogeny; Thrombocytopenia / blood diagnosis virology; Ticks / physiology virology; Travel

Abstract

The Xinjiang Uygur Autonomous Region locating in Northwest of China was not considered the epidemic area of severe fever with thrombocytopenia syndrome (SFTS). Here we report the first laboratory-confirmed SFTS case that a female patient had tick bite in Xinjiang and illness onset after returning to Hainan Province. Laboratory tests identified SFTS virus (SFTSV) infection, and the virus was isolated from the patient\'s serum sample. Furthermore, SFTSV prevalence among tick groups was identified, and IgM response to SFTSV from febrile patients was identified. The findings suggested that there have been risks of SFTSV infection due to exposure to ticks in Xinjiang.