通过抑制 NOX4 的表达对肾结石的影响。
关键词: Aspidopterys obcordata NOX4 Obcordata A antiurolithiatic
Mesh : Animals Antioxidants / chemistry pharmacology Apoptosis / drug effects Biphenyl Compounds / pharmacology Calcium Oxalate / chemistry toxicity Cell Survival / drug effects Humans Kidney Calculi / drug therapy genetics pathology Kidney Tubules / drug effects pathology Malpighiaceae / chemistry Mice NADPH Oxidase 4 / genetics Oxidative Stress / drug effects Phorbol Esters / pharmacology Picrates / pharmacology Pyrazoles / pharmacology Pyrazolones Pyridines / pharmacology Pyridones Reactive Oxygen Species / chemistry Saponins / chemistry pharmacology Tocopherols / pharmacology p38 Mitogen-Activated Protein Kinases / genetics
来 源:
DOI:10.3390/molecules24101957
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