关键词: Cosmetic products GC/MS Liquid-liquid extraction Polycyclic aromatic hydrocarbons (PAHs)

Mesh : Consumer Product Safety Cosmetics / analysis chemistry standards Gas Chromatography-Mass Spectrometry / methods Humans Liquid-Liquid Extraction Polycyclic Aromatic Hydrocarbons / analysis

来  源:   DOI:10.1016/j.jpba.2018.12.029   PDF(Sci-hub)

Abstract:
A suitable extraction protocol based on an liquid-liquid extraction with hexane/dimethyl sulfoxide and a GC/MS method were developed and validated to determine the concentration of six prohibited Polycyclic Aromatic Hydrocarbons (PAHs; benzo[a]pyrene; dibenz[a,h]anthracene; benz[a]anthracene; benzo[j]fluoranthene; benzo[k]fluoranthene; chrysene) in lipsticks commissioned by a cosmetic company to a manufacturer. The lipsticks were produced in four different colors. Analyses confirmed the presence of benz[a]anthracene and chrysene only in two colors in a concentration of 9.3-9.4 ng/g. The concentration of PAHs was 250 times lower than what is considered a toxic level on the basis of what reported in the litaraure and guidances for cosmetic ingredients; therefore we could assume that the risk for consumer health was negligeble.
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