{Reference Type}: Journal Article
{Title}: Determination of polycyclic aromatic hydrocarbons in lipstick by gas-chromatography coupled to mass spectrometry: A case history.
{Author}: Roda G;Arnoldi S;Casagni E;Dei Cas M;Silva L;Carini M;
{Journal}: J Pharm Biomed Anal
{Volume}: 165
{Issue}: 0
{Year}: Feb 2019 20
{Factor}: 3.571
{DOI}: 10.1016/j.jpba.2018.12.029
{Abstract}: A suitable extraction protocol based on an liquid-liquid extraction with hexane/dimethyl sulfoxide and a GC/MS method were developed and validated to determine the concentration of six prohibited Polycyclic Aromatic Hydrocarbons (PAHs; benzo[a]pyrene; dibenz[a,h]anthracene; benz[a]anthracene; benzo[j]fluoranthene; benzo[k]fluoranthene; chrysene) in lipsticks commissioned by a cosmetic company to a manufacturer. The lipsticks were produced in four different colors. Analyses confirmed the presence of benz[a]anthracene and chrysene only in two colors in a concentration of 9.3-9.4 ng/g. The concentration of PAHs was 250 times lower than what is considered a toxic level on the basis of what reported in the litaraure and guidances for cosmetic ingredients; therefore we could assume that the risk for consumer health was negligeble.