关键词: bad trip forensic science forensic toxicology magic mushrooms psilocin psilocybin

Mesh : Adolescent Agaricales Bile / chemistry Chromatography, Gas Hallucinogens / adverse effects Humans Male Psilocybin / adverse effects analogs & derivatives analysis Substance-Related Disorders / complications psychology Suicide Vitreous Body / chemistry

来  源:   DOI:10.1111/1556-4029.13982   PDF(Sci-hub)

Abstract:
Fatalities implicating psychedelic mushrooms are not a common clinical situation in everyday forensic medicine. Despite classification as an illegal drug in many countries, psilocybin mushrooms have the reputation of being safe. We report the case of a young man who jumped from a second story balcony under the influence of psilocybin mushrooms. The psilocin assay was performed by gas chromatography coupled to an electron-impact ionization time-of-flight detector (GC-EI-TOF) after solid-phase extraction. Total psilocin was quantified in peripheral and cardiac blood as 60 and 67 ng/mL, respectively, and in urine (2230 ng/mL), bile (3102 ng/mL), and vitreous humor (57 ng/mL). This case report and review of literature highlights the danger of psilocybin mushrooms. Isolated use of psilocybin mushrooms by a regular consumer without psychiatric history, even under \"safe\" circumstances, can lead to a fatal outcome.
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