关键词: APC, antigen-presenting cell Adoptive T cell therapy CAR, chimeric antigen receptor CD4, -8, -80, cluster of differentiation 4, -8, -80 CTL, cytotoxic-T lymphocyte CTLA-4, cytotoxic T-lymphocyte-associated protein 4 Cervical cancer DC, dendritic cell DFS, disease free survival DNA, deoxyribonucleic acid FIGO, International Federation of Gynecology and Obstetrics HLA, human leucocyte antigen HPV, human papilloma virus Human papillomavirus IL-2, interleukin 2 ILT's, Ig-like transcripts Immune checkpoints inhibitors LLO, listerolysin O Lm, Listeria monocytogenes MAGE-A3, melanoma-associated antigen 3 MCH, major histocompatibility complex ORR, objective response rate OS, overall survival PD-1, programmed cell death protein 1 PD-L1, programmed death-ligand 1 PFS, progression free survival RNA, ribonucleic acid SLP, synthetic long-peptide TCR, T-cell receptor TGFβ, transforming growth factor beta TILs, tumor-infiltrating lymphocytes TRAEs, treatment related adverse events Therapeutic vaccines
来 源:
DOI:10.1016/j.rpor.2018.05.001
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