First autochthonous case of canine visceral leishmaniasis in Rondônia, Brazil, a region with no history of visceral leishmaniasis.

• 影响指数: 2.141
• 发表时间: Sep-Oct 2018
• 来源期刊: Rev Soc Bras Med Trop
• DOI: 10.1590/0037-8682-0143-2017
• PMID: 30304285
• 文章类型: Case Reports
• 中科院分区: Q3
• 方向: 医学
• 作者列表: Silva CJD,Mattos CB,Felipin KP,Silva HPJ,Cantanhêde LM,Porrozzi R,Medeiros JF,Ferreira RGM

Mesh: Animals; Antibodies, Protozoan / blood; Brazil / epidemiology; Dog Diseases / diagnosis epidemiology; Dogs; Enzyme-Linked Immunosorbent Assay / veterinary; Fluorescent Antibody Technique, Indirect / veterinary; Leishmania infantum / genetics immunology; Leishmaniasis, Visceral / diagnosis epidemiology veterinary; Male; Polymerase Chain Reaction / veterinary

Abstract

This report describes the first autochthonous case of canine visceral leishmaniasis in Rondônia, northern Brazil. A canine resident of the municipality of Cacoal, with clinical signs and symptoms of visceral leishmaniasis, was treated by a veterinarian. Samples were analyzed by a reference laboratory. Dual-path platform (DPP) assay, indirect immunofluorescence technique (IIT), enzyme-linked immunosorbent assay (ELISA), polymerase chain reaction (PCR), isolation in a culture medium, and direct parasitological analysis were performed. DPP assay, IIT, and ELISA revealed positive results for Leishmania; PCR identified the species as Leishmania infantum. Based on the clinical presentation and test results, canine visceral leishmaniasis was diagnosed.