PDF(Pubmed)
Abstract：
The risk of infection with Anisakis has been recognized for some time, but it is now emerging due to major awareness, better diagnostic techniques, and increasing preference for raw or lightly cooked food. Spain has the second-highest reported incidence after Japan, though the real anisakidosis burden is unknown because of the scarcity of epidemiological data. This study provides a 19-year review of anisakidosis-related hospitalizations describing epidemiological trends and patient characteristics.
We performed a retrospective descriptive study using the Spanish Hospitalization Minimum Data Set from 1997 to 2015. Hospitalization rates were calculated and spatial distribution of cases and their temporal behavior were assessed. Clinical characteristics were described, including related codiagnoses and procedures.
A total of 2471 hospital discharges were identified. A continuous increasing trend was observed, with several peaks. Most affected communities were located in the northwest inland part of the country. Almost 54% of hospitalized patients were male, with a mean age of 51.3 years. Median length of stay was 5 days, and the hospitalization median cost around €2900. Fatal outcome occurred in 0.5%. Most frequent codiagnoses were digestive diseases, mainly intestinal obstruction. Urticaria, anaphylactic reaction, and angioneurotic edema were only recorded in 2.2%, 2.4%, and 1.2%, respectively.
Knowing that hospitalization is unusual in anisakidosis, we offer calculations of the real disease burden. Improving disease surveillance in parallel to disease control will be useful both in gaining extended disease knowledge and reducing morbidity and related costs.
We performed a retrospective descriptive study using the Spanish Hospitalization Minimum Data Set from 1997 to 2015. Hospitalization rates were calculated and spatial distribution of cases and their temporal behavior were assessed. Clinical characteristics were described, including related codiagnoses and procedures.
A total of 2471 hospital discharges were identified. A continuous increasing trend was observed, with several peaks. Most affected communities were located in the northwest inland part of the country. Almost 54% of hospitalized patients were male, with a mean age of 51.3 years. Median length of stay was 5 days, and the hospitalization median cost around €2900. Fatal outcome occurred in 0.5%. Most frequent codiagnoses were digestive diseases, mainly intestinal obstruction. Urticaria, anaphylactic reaction, and angioneurotic edema were only recorded in 2.2%, 2.4%, and 1.2%, respectively.
Knowing that hospitalization is unusual in anisakidosis, we offer calculations of the real disease burden. Improving disease surveillance in parallel to disease control will be useful both in gaining extended disease knowledge and reducing morbidity and related costs.
摘要：
Anisakis感染的风险已经被认识了一段时间，但是由于主要的意识，它现在正在出现，更好的诊断技术，以及对生的或轻度煮熟的食物的偏好增加。西班牙是仅次于日本的第二高发病率报告，尽管由于流行病学数据的匮乏，真正的anisakidosis负担尚不清楚。这项研究提供了一个19年的回顾，描述了流行病学趋势和患者特征。
我们使用1997年至2015年的西班牙住院最低数据集进行了回顾性描述性研究。计算住院率，并评估病例的空间分布及其时间行为。描述了临床特征，包括相关的共诊断和程序。
共确认2471家医院出院。观察到持续增加的趋势，有几个高峰。大多数受影响的社区位于该国西北内陆。近54%的住院患者是男性，平均年龄51.3岁。平均逗留时间为5天,住院费用中位数约为2900欧元。死亡结局为0.5%。最常见的共诊断是消化系统疾病，主要是肠梗阻。荨麻疹,过敏反应,血管神经性水肿仅占2.2%，2.4%,和1.2%，分别。
知道anisakidosis住院是不寻常的，我们提供实际疾病负担的计算方法。与疾病控制同时改善疾病监测将有助于获得更多的疾病知识并降低发病率和相关成本。
我们使用1997年至2015年的西班牙住院最低数据集进行了回顾性描述性研究。计算住院率，并评估病例的空间分布及其时间行为。描述了临床特征，包括相关的共诊断和程序。
共确认2471家医院出院。观察到持续增加的趋势，有几个高峰。大多数受影响的社区位于该国西北内陆。近54%的住院患者是男性，平均年龄51.3岁。平均逗留时间为5天,住院费用中位数约为2900欧元。死亡结局为0.5%。最常见的共诊断是消化系统疾病，主要是肠梗阻。荨麻疹,过敏反应,血管神经性水肿仅占2.2%，2.4%,和1.2%，分别。
知道anisakidosis住院是不寻常的，我们提供实际疾病负担的计算方法。与疾病控制同时改善疾病监测将有助于获得更多的疾病知识并降低发病率和相关成本。
