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Abstract：
OBJECTIVE: Our research investigated the relationship between childhood leukemia and breastfeeding in the P. R. of China.
METHODS: We conducted a retrospective case-control study from March 2008 to April 2017 at the Children\'s Hospital of Zhejiang University, Zhejiang province, P. R. of China, which reviewed 958 children who had been diagnosed with leukemia in case group and 785 healthy children in control group. Data were obtained from medical records, and if the medical records were incomplete, we called mothers of children by phone to complete the data.
RESULTS: Breastfeeding reduces the risk of childhood leukemia; the effect is greater, if feeding continued for 7-9 months (p = 0.002). In addition, we suggest that some factors such as maternal age, smoking during pregnancy, abortion history, genetic factors, parents use of hair dye, and the history of using birth control pills before pregnancy can increase the risk of childhood leukemia.
CONCLUSIONS: This study indicates that promoting breastfeeding for 7-9 months may help lower the childhood leukemia incidence. Our study firstly demonstrates that breastfeeding has protective effects against childhood leukemia in the P. R. of China.
BACKGROUND: ALL: Acute lymphocytic leukemia; AML: Acute myeloid leukemia.
METHODS: We conducted a retrospective case-control study from March 2008 to April 2017 at the Children\'s Hospital of Zhejiang University, Zhejiang province, P. R. of China, which reviewed 958 children who had been diagnosed with leukemia in case group and 785 healthy children in control group. Data were obtained from medical records, and if the medical records were incomplete, we called mothers of children by phone to complete the data.
RESULTS: Breastfeeding reduces the risk of childhood leukemia; the effect is greater, if feeding continued for 7-9 months (p = 0.002). In addition, we suggest that some factors such as maternal age, smoking during pregnancy, abortion history, genetic factors, parents use of hair dye, and the history of using birth control pills before pregnancy can increase the risk of childhood leukemia.
CONCLUSIONS: This study indicates that promoting breastfeeding for 7-9 months may help lower the childhood leukemia incidence. Our study firstly demonstrates that breastfeeding has protective effects against childhood leukemia in the P. R. of China.
BACKGROUND: ALL: Acute lymphocytic leukemia; AML: Acute myeloid leukemia.
摘要：
目的：我们的研究调查了中国儿童白血病与母乳喂养之间的关系。
方法：我们于2008年3月至2017年4月在浙江大学儿童医院进行了回顾性病例对照研究。浙江省,P.R.中国，该研究回顾了病例组958名被诊断为白血病的儿童和对照组785名健康儿童。数据来自医疗记录，如果医疗记录不完整,我们打电话给孩子的母亲来完成数据。
结果：母乳喂养降低了儿童白血病的风险；效果更大，如果喂养持续7-9个月（p=0.002）。此外,我们建议一些因素，如产妇年龄，怀孕期间吸烟，流产史,遗传因素,父母使用染发剂，怀孕前使用避孕药的历史会增加儿童白血病的风险。
结论：这项研究表明，促进母乳喂养7-9个月可能有助于降低儿童白血病的发病率。我们的研究首次表明，在中国的P.R.中，母乳喂养对儿童白血病具有保护作用。
背景：全部：急性淋巴细胞白血病；AML：急性髓性白血病。
方法：我们于2008年3月至2017年4月在浙江大学儿童医院进行了回顾性病例对照研究。浙江省,P.R.中国，该研究回顾了病例组958名被诊断为白血病的儿童和对照组785名健康儿童。数据来自医疗记录，如果医疗记录不完整,我们打电话给孩子的母亲来完成数据。
结果：母乳喂养降低了儿童白血病的风险；效果更大，如果喂养持续7-9个月（p=0.002）。此外,我们建议一些因素，如产妇年龄，怀孕期间吸烟，流产史,遗传因素,父母使用染发剂，怀孕前使用避孕药的历史会增加儿童白血病的风险。
结论：这项研究表明，促进母乳喂养7-9个月可能有助于降低儿童白血病的发病率。我们的研究首次表明，在中国的P.R.中，母乳喂养对儿童白血病具有保护作用。
背景：全部：急性淋巴细胞白血病；AML：急性髓性白血病。
