CRISPR - Cas9 及其在帮助控制锥虫科引起的被忽视的热带病方面的潜在应用迷你综述。
关键词: CRISPR-Cas9 Neglected tropical diseases Parasites Trypanosomatidae
Mesh : Animals Anopheles / genetics parasitology CRISPR-Associated Protein 9 / genetics metabolism CRISPR-Cas Systems Cattle Clustered Regularly Interspaced Short Palindromic Repeats Disease Models, Animal Drosophila / genetics parasitology Gene Editing / methods Genome, Protozoan Leishmania / genetics pathogenicity Leishmaniasis / parasitology prevention & control transmission Neglected Diseases / parasitology prevention & control RNA, Guide, CRISPR-Cas Systems / genetics metabolism Trypanosoma / genetics pathogenicity Trypanosomiasis, African / parasitology prevention & control transmission Trypanosomiasis, Bovine / parasitology prevention & control transmission
来 源: DOI:10.1016/j.meegid.2018.02.030