关键词: Ectopic cerebellum Glioneuronal ectopia Intraosseous lesion Occipital bone

Mesh : Cerebral Cortex / pathology Cerebral Ventricle Neoplasms / pathology Choristoma / complications pathology Craniotomy Female Hemifacial Spasm / physiopathology surgery Humans Incidental Findings Middle Aged Occipital Bone / pathology Subarachnoid Space / pathology Tomography, X-Ray Computed Treatment Outcome

来  源:   DOI:10.1186/s13256-017-1394-0

Abstract:
BACKGROUND: Ectopic cerebellar tissue located distantly from the normal cerebellum is very rare, and its pathophysiology remains to be elucidated.
METHODS: We report an extremely rare case of intraosseous ectopic cerebellum detected incidentally at suboccipital craniotomy in a 46-year-old Japanese woman with hemifacial spasm. She had a small bone defect in the occipital bone, which contained a tiny area of soft tissue surrounded by cerebrospinal fluid connecting to the normal subarachnoid space through a dural opening. Histopathology demonstrated cerebellar cortex tissue consisting of molecular and granular cell layers.
CONCLUSIONS: This is the first report of glioneuronal ectopia within the skull bone separated from normal brain tissue, and it is important to distinguish this entity from other osteolytic lesions.
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