PDF(Pubmed)
Abstract：
A large body of evidence supports the notion that incorrect or insufficient nutrition contributes to disease development. A pivotal goal is thus to understand what exactly is appropriate and what is inappropriate in food ingestion and the consequent nutritional status and health. The effective application of these concepts requires the translation of scientific information into practical approaches that have a tangible and measurable impact at both individual and population levels. The agenda for the future is expected to support available methodology in nutrition research to personalize guideline recommendations, properly grading the quality of the available evidence, promoting adherence to the well-established evidence hierarchy in nutrition, and enhancing strategies for appropriate vetting and transparent reporting that will solidify the recommendations for health promotion. The final goal is to build a constructive coalition among scientists, policy makers, and communication professionals for sustainable health and nutritional policies. Currently, a strong rationale and available data support a personalized dietary approach according to personal variables, including sex and age, circulating metabolic biomarkers, food quality and intake frequency, lifestyle variables such as physical activity, and environmental variables including one\'s microbiome profile. There is a strong and urgent need to develop a successful commitment among all the stakeholders to define novel and sustainable approaches toward the management of the health value of nutrition at individual and population levels. Moving forward requires adherence to well-established principles of evidence evaluation as well as identification of effective tools to obtain better quality evidence. Much remains to be done in the near future.
摘要：
大量证据支持不正确或营养不足导致疾病发展的观点。因此，关键目标是了解食物摄入中到底什么是适当的，什么是不适当的，以及随之而来的营养状况和健康。这些概念的有效应用需要将科学信息转化为实用的方法，这些方法在个人和人口层面都具有切实和可衡量的影响。未来的议程预计将支持营养研究中可用的方法，以个性化指南建议，对现有证据的质量进行适当评级，促进遵守营养方面完善的证据体系，并加强适当审查和透明报告的战略，以巩固促进健康的建议。最终目标是在科学家之间建立建设性的联盟，政策制定者,和通信专业人员可持续健康和营养政策。目前,强有力的理由和可用的数据支持根据个人变量的个性化饮食方法，包括性别和年龄,循环代谢生物标志物，食物质量和摄入频率，生活方式变量，如身体活动，和环境变量，包括一个人的微生物组概况。迫切需要在所有利益相关者中做出成功的承诺，以确定在个人和人口层面管理营养健康价值的新颖和可持续的方法。向前迈进需要遵守完善的证据评估原则，并确定有效的工具以获得更高质量的证据。在不久的将来，仍有许多工作要做。
