关键词: Dental unit Epidemiological typing Legionella SBT WGS

Mesh : Aged Colony Count, Microbial / methods Cross Infection / epidemiology microbiology mortality Dental Offices / standards Electrophoresis, Gel, Pulsed-Field / methods Fatal Outcome Hospitalization Humans Immunocompromised Host Legionella pneumophila / classification genetics growth & development isolation & purification Legionellosis / diagnosis epidemiology microbiology mortality Legionnaires' Disease / diagnosis microbiology urine Male Serotyping / methods Sweden / epidemiology Water Microbiology Whole Genome Sequencing / methods

来  源:   DOI:10.1016/j.jhin.2017.01.009   PDF(Sci-hub)

Abstract:
In 2012, an elderly immunocompromised man died from legionellosis at a hospital in Uppsala, Sweden. The patient had visited a dental ward at the hospital during the incubation period. Legionella spp. at a concentration of 2000 colony-forming units/L were isolated from the cupfiller outlet providing water for oral rinsing. Isolates from the patient and the dental unit were Legionella pneumophila serogroup 1, subgroup Knoxville and ST9. Pulsed-field gel electrophoresis and whole-genome sequencing strongly suggested that the isolates were of common origin. This report presents one of few documented cases of legionellosis acquired through a dental unit.
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