关键词: Digestion Haematophagy Immunity Mosquitoes Proteases Ticks Triatomines Yolk formation

Mesh : Aged Animals Arthropod Proteins / metabolism Arthropod Vectors / enzymology immunology physiology Egg Yolk / metabolism Feeding Behavior Humans Peptide Hydrolases / metabolism

来  源:   DOI:10.1186/s13071-017-2005-z   PDF(Sci-hub)

Abstract:
Ticks, triatomines, mosquitoes and sand flies comprise a large number of haematophagous arthropods considered vectors of human infectious diseases. While consuming blood to obtain the nutrients necessary to carry on life functions, these insects can transmit pathogenic microorganisms to the vertebrate host. Among the molecules related to the blood-feeding habit, proteases play an essential role. In this review, we provide a panorama of proteases from arthropod vectors involved in haematophagy, in digestion, in egg development and in immunity. As these molecules act in central biological processes, proteases from haematophagous vectors of infectious diseases may influence vector competence to transmit pathogens to their prey, and thus could be valuable targets for vectorial control.
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