METHODS: All the cases presented with fever and some had splenomegaly, bradycardia, abdominal pain and diarrhoea. The epidemic was investigated by the station health organization (SHO) and the case and bacteriological study was carried out in pathology laboratory of the service hospital. The serological study was carried out at Armed Forces Medical College (AFMC), Pune and the Phage typing was carried out at Lady Harding Medical College, New Delhi.
RESULTS: Blood cultures were positive in 92(63%) for Salmonella typhi and Widal test was positive in 83(55%). All strains were resistant to four primary drugs i.e. ampicillin, chloramphenicol, co-trimoxazole and tetracycline. All but two were treated successfully with ceftriaxone. The Salmonella typhi belonged to phage group E1 and biotype I.
CONCLUSIONS: Extensive epidemiological investigation of cases and water sources of cantonment area pointed to a common source of the epidemic i.e. the well near \'Gurudwara\'.
方法:所有病例均表现为发热,部分有脾肿大,心动过缓,腹痛和腹泻。卫生站(SHO)对疫情进行了调查,并在服务医院的病理实验室进行了病例和细菌学研究。血清学研究是在武装部队医学院(AFMC)进行的,浦那和噬菌体打字是在哈丁夫人医学院进行的,新德里。
结果:伤寒沙门氏菌血培养阳性92例(63%),Widal试验阳性83例(55%)。所有菌株对四种主要药物,即氨苄西林,氯霉素,复方新诺明和四环素。除两个外,其他均成功地用头孢曲松治疗。伤寒沙门菌属于噬菌体组E1和生物型I。
结论:对营地地区病例和水源的广泛流行病学调查指出了该流行病的常见来源,即“Gurudwara”附近的井。