{Reference Type}: Journal Article
{Title}: Outbreak of Multi-drug Resistant Salmonella Typhi Enteric Fever in Mumbai Garrison.
{Author}: Misra RN;Bawa KS;Magu SK;Bhandari S;Nagendra A;Menon PK;
{Journal}: Med J Armed Forces India
{Volume}: 61
{Issue}: 2
{Year}: Feb 2005
暂无{DOI}: 10.1016/S0377-1237(05)80011-5
{Abstract}: <B>BACKGROUND: </B>There was an epidemic of enteric fever in Mumbai garrison during Nov-Dec 2000 with more than 150 cases admitted to a tertiary care service hospital.<BR><B>METHODS: </B>All the cases presented with fever and some had splenomegaly, bradycardia, abdominal pain and diarrhoea. The epidemic was investigated by the station health organization (SHO) and the case and bacteriological study was carried out in pathology laboratory of the service hospital. The serological study was carried out at Armed Forces Medical College (AFMC), Pune and the Phage typing was carried out at Lady Harding Medical College, New Delhi.<BR><B>RESULTS: </B>Blood cultures were positive in 92(63%) for Salmonella typhi and Widal test was positive in 83(55%). All strains were resistant to four primary drugs i.e. ampicillin, chloramphenicol, co-trimoxazole and tetracycline. All but two were treated successfully with ceftriaxone. The Salmonella typhi belonged to phage group E1 and biotype I.<BR><B>CONCLUSIONS: </B>Extensive epidemiological investigation of cases and water sources of cantonment area pointed to a common source of the epidemic i.e. the well near 'Gurudwara'.