PDF(Sci-hub)
Abstract：
We write to report a rare case of unilateral cancer-associated retinopathy previously undocumented in the literature. Cancer-associated retinopathy is an uncommon paraneoplastic syndrome. It is characterised by retinal antigen autoantibodies causing rod and cone dysfunction and abnormal electroretinography findings with consequent progressive visual loss.Our patient, known to have a primary cervical intraepithelial neoplasia, presented with unilateral blurred vision as well as a disturbance in colour and night vision. Electroretinography findings of reduced a and b waves in the right eye, together with a fundoscopic appearance of a mottled retinal pigment epithelium, attenuated blood vessels and optic disc pallor were consistent with unilateral cancer-associated retinopathy. Posterior subtenon injections of triamcinolone were administered to control active disease. With periocular steroid injections, at 4 years, our patient\'s visual acuity remained relatively stable and her condition persisted strictly unilaterally. Cancer-associated retinopathy may be the first presenting sign of an underlying malignancy or may indicate its recurrence. Moreover, in patients with a diagnosed gynaecological malignancy, visual symptoms could reflect cancer-associated retinopathy. In our patient visual symptoms came secondary to the diagnosis of cancer.
摘要：
我们撰写报告了一个罕见的单侧癌症相关视网膜病变病例，以前文献中没有记载。癌症相关视网膜病是一种罕见的副肿瘤综合征。它的特征是视网膜抗原自身抗体导致视杆和视锥功能障碍以及异常的视网膜电图检查结果，从而导致进行性视力丧失。我们的病人,已知患有原发性宫颈上皮内瘤变，表现为单侧视力模糊以及颜色和夜视障碍。视网膜电图发现右眼a波和b波减少，以及斑驳的视网膜色素上皮的眼底镜检查外观，减弱的血管和视盘苍白与单侧癌症相关视网膜病变一致.给予曲安奈德后肌腱下注射以控制活动性疾病。眼周注射类固醇，四年后，我们的患者的视力保持相对稳定，她的病情严格单方面持续。癌症相关的视网膜病变可能是潜在恶性肿瘤的第一个表现，也可能表明其复发。此外，在诊断为妇科恶性肿瘤的患者中，视觉症状可以反映癌症相关的视网膜病变.在我们的患者中，视觉症状继发于癌症的诊断。
