由 zDHHC17 / 13 S - 酰基转移酶的 Ankyrin 重复结构域识别的新型序列基序的鉴定。
关键词: Golgi Huntington disease S-acylation ankyrin repeat domain membrane enzyme protein palmitoylation substrate specificity zDHHC13 zDHHC17
Mesh : Acylation Acyltransferases / classification genetics metabolism Amino Acid Motifs / genetics Amino Acid Sequence Animals Ankyrin Repeat / genetics Binding Sites / genetics Blotting, Western Cattle HEK293 Cells HSP40 Heat-Shock Proteins / genetics metabolism Humans Huntingtin Protein Membrane Proteins / genetics metabolism Mice Microtubule-Associated Proteins / genetics metabolism Molecular Sequence Data Mutation Nerve Tissue Proteins / genetics metabolism Phylogeny Protein Binding Rats Sequence Homology, Amino Acid Synaptosomal-Associated Protein 25 / genetics metabolism Zinc Fingers / genetics
来 源:
DOI:10.1074/jbc.M115.657668
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