关键词: Antiangiogenic activity BSA Bovine serum album CAM Chorioallantoic membrane Dissociation E. Coli EC EGF ELISA Endothelial cells Enzyme linked immunosorbent assay Epidermal growth factor Equilibrium constant Escherichia coli FBS FGF Fetal bovine serum Fibroblast growth factors IFN-γ Interferon-γ K(a) K(d) KD KDR Kinase-insert domain-containing receptor (as it is called in human) Monoclonal antibody Periplasmic expression SPR Surface plasmon resonance TNF-α The kinetic constant for association Tumor necrosis factor-α VEGF VEGF receptor-2 VEGFR-2 VEGFR2 Vascular endothelial growth factor mAB
Mesh : Angiogenesis Inhibitors / chemistry pharmacokinetics pharmacology Cell Movement / drug effects Cell Proliferation / drug effects Cells, Cultured Chorioallantoic Membrane / drug effects Endothelium, Vascular / drug effects Humans Peptide Fragments / chemistry pharmacokinetics pharmacology Protein Structure, Tertiary Solubility Transfection Vascular Endothelial Growth Factor A / antagonists & inhibitors pharmacology Vascular Endothelial Growth Factor Receptor-2 / chemistry
来 源:
DOI:10.1016/j.biopha.2013.06.001
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