Mesh : Aged Aged, 80 and over Amino Acids / adverse effects therapeutic use Antipsychotic Agents / adverse effects therapeutic use Cholinesterase Inhibitors / adverse effects therapeutic use Cognition Disorders / diagnosis drug therapy Cross-Sectional Studies Dementia / diagnosis drug therapy epidemiology etiology Drug Therapy, Combination Evidence-Based Medicine Female Ginkgo biloba Humans Incidence Life Style Long-Term Care Male Medication Adherence Memantine / adverse effects therapeutic use Middle Aged Nootropic Agents / therapeutic use Plant Extracts / adverse effects therapeutic use Population Dynamics Psychotropic Drugs / adverse effects therapeutic use Randomized Controlled Trials as Topic