Mesh : Bone Density Bone Density Conservation Agents / therapeutic use Cholecalciferol / therapeutic use Diphosphonates / therapeutic use Evidence-Based Medicine Fractures, Bone / etiology prevention & control Glucocorticoids / administration & dosage adverse effects Humans Japan Osteoporosis / chemically induced complications drug therapy prevention & control Practice Guidelines as Topic Prednisolone / administration & dosage adverse effects Time Factors Vitamin K 2 / therapeutic use