Mesh : Adult Consanguinity Humans Infertility, Male / etiology pathology physiopathology Male Microscopy, Electron Sperm Count Sperm Motility Sperm Tail / ultrastructure Spermatozoa / abnormalities

来  源:   DOI:10.1016/j.fertnstert.2003.10.048   PDF(Sci-hub)

Abstract:
OBJECTIVE: To report a case of 100% teratozoospermia in a patient whose family history presented a high degree of consanguinity.
METHODS: Case report.
METHODS: University-based andrology clinic.
METHODS: A 27-year-old man undergoing infertility evaluation.
METHODS: None.
METHODS: Serum hormone analysis, standard (World Health Organization) semen quality evaluation, sperm ultrastructure, lymphocytic karyotype, and polymerase chain reaction screening for Y chromosome microdeletions in peripheral blood.
RESULTS: One hundred percent teratozoospermia characterized by shape alterations of the heads and tail agenesis on standard morphology evaluation, which was confirmed using electron microscopy.
CONCLUSIONS: A case of familial infertility in a consanguineous patient characterized by morphological abnormalities of spermatozoa such as tail agenesis, chromatin subcondensation, and residual cytoplasmic droplets.
摘要:
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