%0 Case Reports
%T Sperm tail agenesis in a case of consanguinity.
%A Latini M
%A Gandini L
%A Lenzi A
%A Romanelli F
%J Fertil Steril
%V 81
%N 6
%D Jun 2004
%M 15193497
%F 7.49
%R 10.1016/j.fertnstert.2003.10.048
%X <B>OBJECTIVE: </B>To report a case of 100% teratozoospermia in a patient whose family history presented a high degree of consanguinity.<BR><B>METHODS: </B>Case report.<BR><B>METHODS: </B>University-based andrology clinic.<BR><B>METHODS: </B>A 27-year-old man undergoing infertility evaluation.<BR><B>METHODS: </B>None.<BR><B>METHODS: </B>Serum hormone analysis, standard (World Health Organization) semen quality evaluation, sperm ultrastructure, lymphocytic karyotype, and polymerase chain reaction screening for Y chromosome microdeletions in peripheral blood.<BR><B>RESULTS: </B>One hundred percent teratozoospermia characterized by shape alterations of the heads and tail agenesis on standard morphology evaluation, which was confirmed using electron microscopy.<BR><B>CONCLUSIONS: </B>A case of familial infertility in a consanguineous patient characterized by morphological abnormalities of spermatozoa such as tail agenesis, chromatin subcondensation, and residual cytoplasmic droplets.