Mesh : Animals Apoptosis / drug effects Benzamides Cell Line Cell Line, Transformed Cell Transformation, Neoplastic Down-Regulation / drug effects Drug Resistance, Neoplasm / drug effects Drug Synergism Fusion Proteins, bcr-abl Humans Imatinib Mesylate Interferon Regulatory Factors Leukemia, Myelogenous, Chronic, BCR-ABL Positive / drug therapy etiology genetics Male Mice Multipotent Stem Cells Piperazines / pharmacology Promoter Regions, Genetic / drug effects Protein-Tyrosine Kinases / antagonists & inhibitors genetics Proto-Oncogene Proteins c-bcl-2 / biosynthesis genetics Pyrimidines / pharmacology Repressor Proteins / genetics pharmacology physiology Transfection
来 源:
DOI:10.1182/blood-2003-08-2970
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