• 文章类型: Case Reports
    人类免疫缺陷病毒的流行在全球范围内呈上升趋势。药物相关的尿路结石通常是由用于治疗HIV阳性患者的药物引起的。我们介绍了一例HIV阳性的39岁男性,患有输尿管支架结壳和肾结石。使用一次性输尿管软镜进行输尿管碎石术。术后进展良好。一次性输尿管软镜可有效治疗HIV合并输尿管支架结壳。
    Human immunodeficiency virus prevalence was increasing worldwide. Medication-associated urinary calculi are very commonly caused by medications used to treat HIV-positive patients. We present a case of an HIV-positive 39-year-old male with ureteral stent encrustation and kidney stone. Ureterolithotripsy using a disposable flexible ureteroscope is performed. The postoperative evolution was favorable. The disposable flexible ureteroscope is effective in the treatment of HIV combined with ureteral stent encrustation.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

       PDF(Pubmed)

  • 文章类型: Journal Article
    尿路上皮癌的治疗随着腹腔镜或机器人手术等微创技术的引入而发展。挑战传统的开放手术方法,并导致非典型复发(AR)。AR包括端口部位转移和腹膜癌,然而,作者之间在精确分类方面仍然存在差异.AR的发病率在不同的研究中差异很大,在肌肉浸润性膀胱癌(MIBC)和上尿路上皮肿瘤(UTUC)中,范围从不到1%到超过10%。腹膜转移是MIBC患者中最常见的AR,而由于不同的手术方法,腹膜后转移在UTUC患者中普遍存在。AR表现的时间和生存结果与传统复发的时间密切相关,他们经常与之联系在一起。气腹逐渐被认为是ARs的病因,而与手术相关的危险因素越来越突出。目前与手术相关的主要原因包括手术期间肿瘤溢出和尿路侵犯,避免使用endo袋进行标本提取,和低手术经验。肿瘤分期等因素,组织学变异,和淋巴血管侵犯与ARs的风险相关,表明与肿瘤生物学密切相关。需要进一步的研究来更好地了解发病率,危险因素,特点,和AR的结果。
    The management of urothelial carcinoma has evolved with the introduction of minimally invasive techniques such as laparoscopic or robotic procedures, challenging the traditional approach of open surgery, and giving rise to atypical recurrences (ARs). ARs include port-site metastasis and peritoneal carcinomatosis, yet discrepancies persist among authors regarding their precise classification. Incidence rates of ARs vary widely across studies, ranging from less than 1% to over 10% in both muscle-invasive bladder cancer (MIBC) and upper tract urothelial tumor (UTUC). Peritoneal metastases predominate as the most common ARs in patients with MIBC, while retroperitoneal metastases are prevalent in those with UTUC due to differing surgical approaches. The timing of AR presentation and survival outcomes closely mirror those of conventional recurrences, with which they are frequently associated. Pneumoperitoneum has progressively been regarded less as the cause of ARs, while surgical-related risk factors have gained prominence. Current major surgical-related causes include tumor spillage and urinary tract violation during surgery, avoidance of endo bag use for specimen extraction, and low surgical experience. Factors such as tumor stage, histological variants, and lympho-vascular invasion correlate with the risk of ARs, suggesting a close association with tumor biology. Further studies are required to better understand the incidence, risk factors, characteristics, and outcomes of ARs.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

       PDF(Pubmed)

  • 文章类型: Journal Article
    背景和目的:这项研究评估了通过将球囊导管通过猪尾肾造口术引流导管插入球囊导管而形成的单通路途径联合尿路改道的有效性和安全性。通过这种方法,我们的目标是为输尿管漏患者提供一种替代方案,这些患者是不理想的手术选择.材料和方法:这项回顾性研究包括9例患者(其中8例为双侧病例,1例为单侧病例,总计17例),在2023年9月至2024年3月期间接受了手术。该方法涉及经皮进入骨盆系统,通过猪尾肾造口术导管插入4-FrenchFogarty球囊导管,并在输尿管近端或中段充气。结果:17例均获得技术成功,无重大并发症。该程序有效缓解了大多数患者与尿漏相关的症状。然而,5例(29.4%)发生球囊导管显著放气,三个(17.6%)经历完全通货紧缩。在这五个案例中,最终气球尺寸为5.81毫米(范围:0-8.9毫米),确认从手术前到手术后大小减少了25.0%。输尿管闭塞平均28.3d(范围:8-57d)。所有患者在暂时性输尿管闭塞期间症状缓解。除了两名失去随访的患者,3例患者仅出现PCN症状改善,4例患者在球囊导管拔除之前或之后接受了瘘管手术闭合.结论:本研究证实该方法是安全有效的。
    Background and Objectives: This study evaluated the efficacy and safety of temporary ureteral occlusion combined with urinary diversion using a single-access route created by inserting a balloon catheter through a pigtail nephrostomy drainage catheter. With this approach, we aimed to offer an alternative for patients with ureteral leaks who are suboptimal surgical candidates. Materials and Methods: This retrospective study included nine patients (eight of which were bilateral cases and one was unilateral, totaling seventeen cases) who underwent the surgery between September 2023 and March 2024. The method involved gaining percutaneous access to the pelvicalyceal system, inserting a 4-French Fogarty balloon catheter through a pigtail nephrostomy catheter, and inflating the balloon at the proximal or mid-ureter. Results: All 17 cases achieved technical successful with no major complications. The procedure effectively relieved symptoms associated with urinary leakage in most patients. However, the significant deflation of the balloon catheter occurred in five cases (29.4%), with three (17.6%) experiencing complete deflation. In these five cases, the final balloon size was 5.81 mm (range: 0-8.9 mm), confirming a 25.0% decrease in size from pre- to post-procedure. Ureteral occlusion was 28.3 d long on average (range: 8-57 d). All patients experienced symptom relief during temporary ureteral occlusion. Except for two patients lost to follow-up, three patients showed symptom improvement with only PCN and four patients underwent surgical closure of the fistula tract before or after balloon catheter removal. Conclusions: This study confirms that this approach is safe and effective.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

       PDF(Pubmed)

  • 文章类型: Journal Article
    居民学习膀胱尿道吻合术(VUA),机器人辅助前列腺癌根治术(RARP)的关键步骤,在他们训练的早期。VUA评估和培训显着影响患者的预后,具有很高的教育价值。本研究旨在使用脑电图(EEG)和眼动跟踪数据为机器人吻合能力评估(RACE)指标开发客观的预测模型。使用达芬奇手术机器人对塑料模型和动物组织进行机器人辅助VUA(以下简称“吻合”)的23名参与者记录了数据。提取EEG和眼睛跟踪特征,3名评估者使用RACE工具和手术视频评估参与者的吻合子任务表现。开发了随机森林回归(RFR)和梯度提升回归(GBR)模型来使用提取的特征预测RACE分数,而线性混合模型(LMM)识别特征和RACE评分之间的关联。缺乏经验的总体绩效得分显着不同,主管,和经验丰富的技能水平(P值<0.0001)。对于塑料吻合,预测看不见的测试分数的R2值是:针头定位(0.79),针入口(0.74),针驱动和组织创伤(0.80),缝线放置(0.75),和组织近似(0.70)。对于组织吻合,数值分别为0.62,0.76,0.65,0.68和0.62.该模型可以通过向学员提供客观的表现反馈来增强RARP吻合训练。
    Residents learn the vesico-urethral anastomosis (VUA), a key step in robot-assisted radical prostatectomy (RARP), early in their training. VUA assessment and training significantly impact patient outcomes and have high educational value. This study aimed to develop objective prediction models for the Robotic Anastomosis Competency Evaluation (RACE) metrics using electroencephalogram (EEG) and eye-tracking data. Data were recorded from 23 participants performing robot-assisted VUA (henceforth \'anastomosis\') on plastic models and animal tissue using the da Vinci surgical robot. EEG and eye-tracking features were extracted, and participants\' anastomosis subtask performance was assessed by three raters using the RACE tool and operative videos. Random forest regression (RFR) and gradient boosting regression (GBR) models were developed to predict RACE scores using extracted features, while linear mixed models (LMM) identified associations between features and RACE scores. Overall performance scores significantly differed among inexperienced, competent, and experienced skill levels (P value < 0.0001). For plastic anastomoses, R2 values for predicting unseen test scores were: needle positioning (0.79), needle entry (0.74), needle driving and tissue trauma (0.80), suture placement (0.75), and tissue approximation (0.70). For tissue anastomoses, the values were 0.62, 0.76, 0.65, 0.68, and 0.62, respectively. The models could enhance RARP anastomosis training by offering objective performance feedback to trainees.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

       PDF(Pubmed)

  • 文章类型: Journal Article
    确定可能有助于预测逆行肾内手术(RIRS)期间输尿管入路鞘(UAS)放置成功的放射学参数。该研究包括49名在RIRS中放置输尿管入路鞘失败的患者和49名在2023年1月至2023年12月之间成功放置的对照组患者。年龄,性别,体重指数(BMI),非对比计算机断层扫描(NCCT),比较两组患者的肾输尿管膀胱(KUB)片。测量骨盆入口的前后(ap)直径,骨盆出口前后径,棘突间距离直径取自非对比计算机断层扫描(NCCT),而通过肾输尿管膀胱(KUB)造影测量骨盆前后直径和骨盆外侧直径。两组之间的年龄没有显着差异,性别,身体质量指数,ap骨盆入口直径,ap骨盆出口,和棘突间距离直径。然而,在KUB射线照相上测得的骨盆ap直径和骨盆外侧直径值之间存在统计学上的显着差异。在KUBX射线照片中测量的骨盆直径和骨盆侧向直径的值可用于预测RIRC手术期间UAS通过的可能性。然而,需要对更大的患者群体进行进一步研究以确定临界值.
    To identify the radiological parameters which may help to predict the success of ureteral access sheath (UAS) placement during retrograde intrarenal surgery (RIRS).The study included 49 patients in whom failure ureteral access sheath placement in RIRS and 49 control group patients who were successfully placement between January 2023 and December 2023. The age, gender, body mass index (BMI), non-contrast computed tomography (NCCT), and kidney ureter bladder (KUB) radiographs were compared between the two groups. Measurements of the anteroposterior (ap) diameter of the pelvic inlet, anteroposterior diameter of the pelvic outlet, interspinous distance diameter were taken from non-contrast computed tomography (NCCT), while pelvic anteroposterior diameter and pelvic lateral diameter were measured from kidney ureter bladder (KUB) radiography. There were no significant differences between the groups in age, gender, body mass index, ap pelvic inlet diameter, ap pelvic outlet, and interspinous distance diameter. However, a statistically significant difference was found between the pelvic ap diameter and pelvic lateral diameter values measured on the KUB radiography. The values for pelvic ap diameter and pelvic lateral diameter measured in the KUB radiographs can be used to predict the likelihood of UAS passage during RIRC procedures. However, further studies with larger patient groups are needed to establish a cut-off value.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

       PDF(Pubmed)

  • 文章类型: Journal Article
    背景:上尿路尿路上皮癌(UTUC)是一种罕见的恶性肿瘤,通常每个泌尿科每年只有很少的新病例。在北欧国家,是否遵守欧洲泌尿外科协会(EAU)关于UTUC的指南是未知的。这项调查的目的是审查EAU准则的执行情况,北欧国家UTUC治疗的围手术期管理和组织。
    方法:对北欧国家进行根治性肾输尿管切除术(NU)的93家医院进行了电子调查。调查由57个主要问题组成,数据收集于12月1日之间,2021年4月23日,2022年。
    结果:总有效率为47/93(67%),完成率为98%。≥72%的参与中心采用了6名接受诊断实践的受试者中的5名。NU作为高风险UTUC的治疗由37/47(79%)进行,91%包括膀胱袖套切除。
    结论:在北欧国家的诊断实践中,遵守EAU指南的程度很高,而疾病管理则不那么连贯。
    BACKGROUND: Upper tract urothelial carcinoma (UTUC) is a rare malignancy, with typically only few new cases annually per urological department. Adherence to European association of urology (EAU) guidelines on UTUC in the Nordic countries is unknown. The objective of this survey was to examine the implementation of EAU guidelines, the perioperative management and organization of the treatment of UTUC in the Nordic countries.
    METHODS: The electronic survey was distributed to 93 hospitals in the Nordic countries performing radical nephroureterectomy (NU). The survey consisted of 57 main questions and data was collected between December 1st, 2021 and April 23rd, 2022.
    RESULTS: Overall response rate was 47/93 (67%) with a completion rate of 98%. Five out of the 6 examined subjects on diagnostic practice are applied by ≥ 72% of the participating centers. NU as treatment for high-risk UTUC is performed by 37/47 (79%), and 91% include a bladder cuff excision.
    CONCLUSIONS: Adherence to EAU guidelines is high on diagnostic practice in the Nordic countries, whereas disease management is less coherent.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

       PDF(Pubmed)

  • 文章类型: Case Reports
    一个9岁的孩子,斯派德,雌性家养短腿猫出现约1厘米大小的开放性伤口,暴露于左侧皮下输尿管旁路术(SUB)分流端口,该端口在出现前约11个月放置。在进行局部伤口处理并重新定位端口之前,尝试了两次初次闭合。在凹陷和重新定位之前,用聚己内酯和丙基甜菜碱伤口冲洗溶液局部冲洗暴露的端口,导致植入物的成功保留。在修订和省略五个月后,伤口完全覆盖和愈合。
    适当的局部治疗,对于SUB分流口挤压继发于泌尿道耐药局部感染的罕见并发症,重新定位和穿孔可能是一种成功的治疗选择。
    UNASSIGNED: A 9-year-old, spayed, female domestic shorthair cat presented with an open wound approximately 1 cm in size with exposure of the left subcutaneous ureteral bypass (SUB) shunting port that was placed approximately 11 months before presentation. Primary closures were attempted twice before local wound management with omentalisation and repositioning of the port. The exposed port was lavaged topically with a polyhexanide and propylbetaine wound irrigation solution before omentalisation and repositioning, resulting in successful retention of the implant. Five months after revision and omentalisation, there was complete coverage and healing of the wound.
    UNASSIGNED: Adequate topical treatment, repositioning and omentalisation could be a successful treatment option for the uncommon complication of SUB shunting port extrusion secondary to resistant local infection originating from the urinary tract.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

       PDF(Pubmed)

  • DOI:
    文章类型: Journal Article
    为了证明我们在输尿管镜检查和钬激光碎石术治疗上尿路结石的初步经验的结果。
    在Awka一家私人泌尿科中心接受输尿管镜检查和激光碎石术治疗上尿路结石的32名患者的数据,对尼日利亚阿南布拉州从2020年9月至2022年6月(20个月)进行了回顾性研究。他们的社会人口统计数据,临床症状,石头的位置和大小,术前和术后使用支架,住院,并发症,分析结石清除率。
    共对32例患者进行了32次手术。患者的平均年龄为44.7±12.2岁。平均结石大小为15.4±6.7mm,范围为8.0-39mm,和Hounsfield单位从233-906。石头在正确的地方,左道,双边占46.9%,43.7%,和9.4%的病例。患者的平均住院时间为3.31±1.45天。结石清除率为90.3%。53.1%的患者有术后并发症,其中40.6%是术后发热,并用抗生素解决。一名患者因输尿管狭窄而无法检查输尿管,导致治疗失败。
    输尿管镜和激光碎石术是治疗上消化道结石的安全有效的选择,具有通过自然孔口进行的优点,不那么痛苦,降低严重出血的风险,肾实质的不可逆损失,以及短暂的住院时间。
    UNASSIGNED: To demonstrate the outcome of our initial experience in the management of upper tract stones with ureteroscopy and Holmium: YAG laser lithotripsy.
    UNASSIGNED: The data of thirty-two patients who had ureteroscopy and laser lithotripsy for upper urinary tract stones at a private urology centre in Awka, Anambra State Nigeria from September 2020 to June 2022 (20months) were retrospectively studied. Their sociodemographic data, clinical symptoms, the location and size of the stones, preoperative and postoperative stent use, hospital stay, complications, and stone-clearance rates were analyzed.
    UNASSIGNED: A total of 32 procedures were performed on 32 patients. The mean age of the patients was 44.7 ± 12.2 years. The mean stone size was 15.4 ± 6.7mm with a range of 8.0-39mm, and Hounsfield unit ranging from 233-906. The stones were on the right tract, left tract, and bilateral in 46.9%, 43.7%, and 9.4% of the cases respectively. The patients had a mean length of hospital stay of 3.31 ± 1.45 days. The stone clearance rate was 90.3%. 53.1% of the patients had postoperative complications with 40.6% of these being post-operative fever which resolved with antibiotics. There was treatment failure in one patient due to the inability to scope the ureter on account of ureteral stricture.
    UNASSIGNED: Ureteroscopy and laser lithotripsy are safe and effective options in the management of upper tract stones with the advantages of being performed via a natural orifice, being less painful, with reduced risk of severe bleeding, irreversible loss of renal parenchyma, as well as a short hospital stay.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

       PDF(Pubmed)

  • 文章类型: Journal Article
    评估机器人辅助的根治性肾输尿管切除术(RARNU)在老年和年轻上呼吸道尿路上皮癌(UTUC)患者中的肿瘤疗效和安全性。单中心,回顾性队列研究于2009年至2022年进行,纳入了145例接受RARNU治疗的非转移性UTUC患者(两组:<75岁和≥75岁).主要终点是监测期间与UTUC相关的疾病复发(膀胱特异性和转移性)。根据30天评估安全性,修改的Clavien-Dindo(CD)分类(主要:C.D.III-V)。使用Kaplan-Meier方法进行生存估计。有89例患者<75岁(中位数65岁)和56例患者≥75岁(中位数81岁)。比较年轻和老年队列:中位随访38vs24个月(分别为p=0.03),3年膀胱特异性复发生存率相似(60%vs67%,HR0.70,95%CI[0.35,1.40],p=0.31)和无转移生存率(79%vs70%,HR0.71,95%CI[0.30,1.70],p=0.44)。期望,与1年(89%vs76%)和3年(72%vs41%;HR3.29,95%CI[1.88,5.78]相比,较年轻的队列在总生存率上有显著差异,p<0.01)。30天主要并发症(1%vs0)和次要并发症(8%vs14%,p=0.87)。局限性包括大量的回顾性研究设计,单外科医生的经验。与年轻的UTUC患者相比,接受RARNU的老年患者在中期随访时的肿瘤学结局相似,30日围手术期并发症的风险没有增加.因此,不应单凭年龄就取消患者接受RARNUUTUC的明确手术治疗的资格.
    To assess the oncologic efficacy and safety of robot-assisted approach to radical nephroureterectomy (RARNU) in geriatric versus younger patients with upper tract urothelial carcinoma (UTUC). A single-center, retrospective cohort study was conducted from 2009 to 2022 of 145 patients (two cohorts: < 75 and ≥ 75 years old) with non-metastatic UTUC who underwent RARNU. Primary endpoint was UTUC-related recurrence of disease during surveillance (bladder-specific and metastatic). Safety was assessed according to 30-day, modified Clavien-Dindo (CD) classifications (Major: C.D. III-V). Survival estimates were performed using Kaplan-Meier method. There were 89 patients < 75 years (median 65 years) and 56 patients ≥ 75 years (median 81 years). Comparing the young versus geriatric cohorts: median follow-up 38 vs 24 months (p = 0.03, respectively) with similar 3-year bladder-specific recurrence survival (60% vs 67%, HR 0.70, 95% CI [0.35, 1.40], p = 0.31) and metastasis-free survival (79% vs 70%, HR 0.71, 95% CI [0.30, 1.70], p = 0.44). Expectedly, the younger cohort had a significant deviation in overall survival compared to the geriatric cohort at 1-year (89% vs 76%) and 3-years (72% vs 41%; HR 3.29, 95% CI [1.88, 5.78], p < 0.01). The 30-day major (1% vs 0) and minor complications (8% vs 14%, p = 0.87). Limitations include retrospective study design of a high-volume, single-surgeon experience. Compared to younger patients with UTUC, geriatric patients undergoing RARNU have similar oncologic outcomes at intermediate-term follow-up with no increased risk of 30-day perioperative complications. Thus, age alone should not be used to disqualify patients from definitive surgical management of UTUC with RARNU.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

       PDF(Pubmed)

  • 文章类型: Journal Article
    经肛门全直肠系膜切除术(taTME)改善了狭窄骨盆中直肠癌的腹腔镜解剖。尽管taTME比腹腔镜手术有更多的临床益处,例如更好地了解直肠远端和直接确定远端切除边缘,在ta-TME切除术中可能发生术中尿道损伤。本研究旨在确定TA-TME与IRISU试剂盒手术的可行性和有效性。这项回顾性研究纳入了10名直肠癌患者,这些患者接受了IRISU试剂盒的taTME。研究终点是进入的安全性(术中或术后发病率)。通过使用腹腔镜-ICG荧光摄像机系统研究了IRISU套件导管的可检测性。他们的平均年龄为71.4±6.4(58-78)岁;80为男性,两个是女人。平均手术时间为534.6±94.5分钟。结肠吻合术占80%,20%的患者接受了腹部腹膜切除术。两名患者遇到了Clavien-Dindo2级的术后并发症。使用IRISU套件辅助的经肛门入路是可行的,对于下直肠癌患者是安全的,并可防止术中尿道损伤。
    Transanal total mesorectal excision (taTME) has improved the laparoscopic dissection for rectal cancer in the narrow pelvis. Although taTME has more clinical benefits than laparoscopic surgery, such as a better view of the distal rectum and direct determination of distal resection margin, an intraoperative urethral injury could occur in excision ta-TME. This study aimed to determine the feasibility and efficacy of the ta-TME with IRIS U kit surgery. This retrospective study enrolled 10 rectal cancer patients who underwent a taTME with an IRIS U kit. The study endpoints were the safety of access (intra- or postoperative morbidity). The detectability of the IRIS U kit catheter was investigated by using a laparoscope-ICG fluorescence camera system. Their mean age was 71.4±6.4 (58-78) years; 80 were men, and 2 were women. The mean operative time was 534.6 ± 94.5 min. The coloanal anastomosis was performed in 80%, and 20% underwent abdominal peritoneal resection. Two patients encountered postoperative complications graded as Clavien-Dindo grade 2. The transanal approach with IRIS U kit assistance is feasible, safe for patients with lower rectal cancer, and may prevent intraoperative urethral injury.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

       PDF(Pubmed)

公众号